Low Birth Weight and Preterm Births among Infants Born to Women Living near a Municipal Solid Waste Landfill Site in Montréal, Québec
Référence bibliographique 
Golberg, Mark S., Goulet, Lise, Riberdy, Hélène et Bonvalot, Yvette. 1995. «Low Birth Weight and Preterm Births among Infants Born to Women Living near a Municipal Solid Waste Landfill Site in Montréal, Québec ». Environmental Research, vol. 69, p. 37-50.
Intentions : «We have been investigating health effects among persons living near the Miron Quarry MSW landfill site in Montreal, Quebec. Given the possibility that exposure to biogas may cause adverse reproductive effects, even though exposure levels are expected to be low, we conducted the current investigation in order to determine whether rates of low birth weight, very low birth weight, small for gestational age, and preterm birth among women living near the site were higher than expected. » (p. 38)
Échantillon/Matériau : All live births occurring among residents of the Island of Montreal between 1979 and 1989 inclusive, were eligible for the study. Births were identified using the birth registration file to the province of Quebec. There were a total of 277,347 live births during the 11 year period. In total, 150,692 births were excluded. Of the 126,655 births available for analysis, excluding missing values (less than 1% of the data), 5.79% of boys and 6.88% of girls were born with low birth weight ((2500 g), 0.77% of boys and 0.72% of girls were born with very low birth weight ((1500 g), 6,18% of boys and 5.5% of gilrs were preterm births ((37 completed weeks gestation), and 5,48% of boys and 5.24% of gilrs were declared to be small for their gestational age.
Instruments : Birth registration file of the province of Quebec
Type de traitement des données : Analyse statistique
« Using data from the Quebec birth registration file, case-control analysis were conducted in order to evaluate the risk of low birth weight ((2500 g), very low birth weight ((1500 g), preterm birth ((37 completed weeks), and small for gestional age (( third percentile) among infants born to women living near a municipal solid waste landfill site in a densely populated area of Montreal, Quebec. Potential exposure to vapors and gases (biogas) was defined in terms in terms of exposure zones around the site. A set of reference areas was selected to be similar to these exposure zones on a number of key sociodemographic factors. Odds ratios (OR) adjusted for variables on the birth file were calculated using logistic regression. Low birth weight was significantly elevated in the exposure zone proximal to the site (adjusted OR = 1.20; 1107 exposed cases; 95% confidence interval: 1.04-1.39). Excess risks were also observed for small for gestational age, but the association was not as strong as for low birth weight (adjusted OR= 1.09; 951 exposed cases; 95% confidence interval: 0.96- 1.24). No significant positive associations were observed for very low birth weight of for preterm birth. Because it was not possible to evaluate the effects of all potentially important confounding factors and because detailed environmental exposure assessments were not available, it is not possible to conclude definitively whether low birth weight and small for gestational age are associated with exposure to biogas. Further studies at this and at other landfill sites are warranted in order to confirm or refute these observations and to investigate other possible adverse reproductive outcomes. » (p. 37)