Demogenetic Study of Three Populations within a Region with Strong Founder Effects

Demogenetic Study of Three Populations within a Region with Strong Founder Effects

Demogenetic Study of Three Populations within a Region with Strong Founder Effects

Demogenetic Study of Three Populations within a Region with Strong Founder Effectss

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Référence bibliographique [3644]

Lavoie, Eve-Marie, Tremblay, Marc, Houde, Louis et Vézina, Hélène. 2005. «Demogenetic Study of Three Populations within a Region with Strong Founder Effects ». Community Genetics, vol. 8, no 3, p. 152-160.

Fiche synthèse

1. Objectifs


Intentions :
« The population of the Saguenay-Lac-St-Jean (SLSJ) region […] is known to have a relatively high prevalence of certain hereditary disorders, which can be explained by the consequences of founder effects. This study aims at providing new insights on the origins and subregional stratification of these founder effects. » (p. 152)

2. Méthode


Échantillon/Matériau :
« The genealogies of 300 individuals were reconstructed and analyzed using the BALSAC population register. » (p. 152)

Type de traitement des données :
Analyse statistique

3. Résumé


« Results : Inbreeding and kinship levels are higher in Lower Saguenay than in Upper Saguenay and Lac-St-Jean. The population of Lower Saguenay also distinguishes itself because of a fewer number of distinct ancestors. Conclusion : Beyond the genetic features that characterize the whole region, SLSJ also displays intraregional variability. Thus it is important to take into account the settlement patterns and the demographic history of this population for a better appraisal of its contemporary genetic structure. » (p. 152)