1. Objectifs

Intentions :
«This paper will explain and discuss some of the potential risk factors of early life adversity (ELA) that display markedly similar outcomes that constitute some of the later symptoms of FM [fibromyalgia].» (p. 310)

2. Méthode

Échantillon/Matériau :
Données documentaires diverses

Type de traitement des données :
Réflexion critique

3. Résumé

«This paper has focused on the evdence showing that painful procedures during early life cause long-lasting changes in pain processing and suggests that high exposure to painful experiences in early life may partially explain the increased pain sensitivity shown by FM patient. In addition, childhood adversities and maternal deprivation are also discussed in terms of the effects they have on stress-regulatory systems in the older organism, so again are potentially sources of the disorders in cortisol level and stress response seen in FM patients. […] Exposure of developing brain to perinatal stress and glucocorticoids during critical periods of development may affect the long-term function of areas involved in stress regulation such as the hippocampus and amygdala and help explain the ''fibrobog'' and anxiety disorders prevalent in FM. Furthermore, impairments in stress regulation caused by early exposure to stressors such as increased maternal cortisol levels, pain, or maternal deprivation may also partially explain the increased pain sensitivities seen in FM patients.» (p. 328-329)