Conjoint Associations of Gestational Diabetes, and Hypertension with Diabetes, Hypertension, and Cardiovascular Disease in Parents
Référence bibliographique 
Pace, Romina. 2017. «Conjoint Associations of Gestational Diabetes, and Hypertension with Diabetes, Hypertension, and Cardiovascular Disease in Parents». Mémoire de maîtrise, Montréal, Université McGill, Département d’épidémiologie, de biostatistique et de santé au travail.
Intentions : This thesis is composed of three manuscripts. This abstract focus on the second manuscript. It «aims to evaluate the relationship of GDM/GH [gestational diabetes/gestational hypertension] to diabetes, hypertension, and CVD [cardiovascular disease] in mothers by combining GDM and GH into a single risk indicator. Given shared couple behaviours, outcomes in fathers were also evaluated.» (p. 67)
Échantillon/Matériau : This second article «uses a large merged data set that includes health administrative, birth registry, and death registry data on 40,000 triads (mother-father-offspring) [from the province of Quebec] with GDM matched to triads without GDM on maternal age, year of delivery and health region.» (p. vii)
Type de traitement des données : Analyse statistique
The findings of this study «support the need for couple-targeted post-partum interventions to decrease cardiometabolic risk in both parents.» (p. 68) «Our results demonstrate that a history of either GDM or GH increases the risk of diabetes, hypertension, and CVD in mothers. A history of both GDM and GH increases risk further across these important outcomes. Specifically, a history of either GDM or GH increased the risk of postpartum diabetes 15-fold and a history of both GDM and GH increased the risk more than 26-fold. […] These results indicate that pregnancy-related metabolic complications signal a need for prevention and surveillance of cardiometabolic disease in mothers and fathers, with particular urgency when both GDM and GH occur. […] We also determined in mothers that GDM or GH alone nearly doubled hypertension risk while the presence of both increased the risk almost 6-fold.» (p. 75-76) Data also shows that «the individual and combined effects of GDM and GH not only in mothers but also in fathers for diabetes incidence. We determined that having a partner who had either GDM or GH resulted in a 20% risk increase in fathers. If the partner had both conditions, there was an 80% risk increase compared to those whose partners had neither pregnancy-associated disorder.» (p. 77)